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Year : 2018  |  Volume : 2  |  Issue : 1  |  Page : 59-63

Cumulus Cells and their Associations with Immune Functions

1 Department of Gynecology and Obstetrics, Johns Hopkins University of Medicine, Maryland 21093, USA
2 Women's Health and Reproductive Medicine Centre, Hong Kong, China

Correspondence Address:
Ping Xia
Department of Gynecology and Obstetrics, Johns Hopkins University of Medicine, 10751 Falls Road, Falls Concourse, Suite 280 Lutherville, Maryland 21093
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2096-2924.232877

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The recent progress in the association of cumulus cells with immune functions is a largely ignored area. With over 350 million new sexually transmitted infections occurring annually in adults of reproductive age, we feel the need to explore more about how the cumulus cells defend themselves and protect the oocytes during the development through the ovulation period. Application of assisted reproductive technologies allows scientists to study and better understand cumulus cells. There are still many immune factors to be taken into consideration to optimize the oocyte quality besides ovarian stimulations. The objective of this review is to summarize the key elements of cumulus cells and their association with the immune function.

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