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  Indian J Med Microbiol
 

Figure 2: ROS and MMP after 24 h incubation with 0–20 μmol/L Vit K3. (a) ROS level was presented as mean fluorescence intensity of DCF in all cells; (b) ROS first decreased from 0 to 5 μmol/L and then increased with concentration from 5 to 10 μmol/L, and there was an ROS surge at 20 μmol/L Vit K3 treatment in PC.12 cells; (c) MMP level was presented as mean fluorescence of TMRE; (d) No changes of MMP were detected in any group. *P < 0.05, P < 0.01. ROS: Reactive oxygen species; MMP: Mitochondrial membrane potential; DCF: Dichlorofluorescin; Vit K3: Vitamin K3; TMER: Tetramethylrhodamine ethyl ester.

Figure 2: ROS and MMP after 24 h incubation with 0–20 μmol/L Vit K3. (a) ROS level was presented as mean fluorescence intensity of DCF in all cells; (b) ROS first decreased from 0 to 5 μmol/L and then increased with concentration from 5 to 10 μmol/L, and there was an ROS surge at 20 μmol/L Vit K3 treatment in PC.12 cells; (c) MMP level was presented as mean fluorescence of TMRE; (d) No changes of MMP were detected in any group. *<i>P</i> < 0.05, <sup>†</sup><i>P</i> < 0.01. ROS: Reactive oxygen species; MMP: Mitochondrial membrane potential; DCF: Dichlorofluorescin; Vit K3: Vitamin K3; TMER: Tetramethylrhodamine ethyl ester.