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Year : 2018  |  Volume : 2  |  Issue : 4  |  Page : 252-255

Mistaken oophorectomy in an adolescent with mccune–Albright syndrome: A case report and literature review

1 Department of Gynecology, Campus Virchow Clinic, Charite Medical University of Berlin, Corporate Member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health; Tumor Bank Ovarian Cancer Network, Berlin, Germany
2 Department of Gynecological Endocrinology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
3 Department of Gynecological Endocrinology, Obstetrics and Gynecology Hospital of Fudan University; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China

Correspondence Address:
Wei Zhang
Department of Gynecological Endocrinology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Shanghai 200011
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2096-2924.249887

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McCune–Albright syndrome (MAS) is a rare disease characterized by café au lait spots, bone fibrous dysplasia, and precocious puberty. Most MAS cases are diagnosed before adolescence. Here, we reported an adolescent girl underwent mistaken oophorectomy for suspected ovarian tumor, and later, she was diagnosed with MAS. An 11-year-old girl was found to have an irregular pelvic mass measuring 9.74 cm × 9.01 cm × 7.30 cm with a cyst–solid component and a clear boundary by magnetic resonance imaging. She underwent right oophorectomy for the suspected ovarian tumor. However, histopathological examination showed ovarian tissue with many antral follicles. One week after the surgery, ultrasonography revealed a left pelvic irregular echo-free mass measuring 60 mm × 53 mm × 48 mm. The patient was then examined by endocrine specialists, and café au lait spots were found predominantly located on the right side of her waist, hip, and thigh. She had her first period before the surgery, and her serum concentrations of sex hormones were normal. Thus, MAS was diagnosed. The patient has been taking dydrogesterone 20 mg/d for 10 days from the 14th day of her period for 2 years. Ultrasonography performed every 3–6 months revealed no enlargement of her left ovary. Awareness of MAS and careful physical and imaging examination should be emphasized, even in the absence of full classic triad of syndromes. Hence, unnecessary oophorectomy and irreversible loss of fertility potential can be avoided in these patients.

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