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  Indian J Med Microbiol
 

Figure 3: Gal-9 increases the expression of MMP-2 by HTR8/SVneo cells. (a and b) Flow cytometric analysis (right) and quantitation (left) of MMP-2 (a) and MMP-2 production (b) by HTR8/SVneo cells after stimulation with or without Gal-9 (1,000 ng/mL) for 48 h. Flow cytometry plot is from one representative experiment. Data represent mean ± standard error of the mean. *P ≥ 0.001. (c and d) Flow cytometric analysis (d) and quantitation (c) of MMP-2 production by HTR8/SVneo cells after stimulation with or without Gal-9 (1,000 ng/mL) in the presence or absence of anti-Gal-9, anti-CD44, or anti-Tim–3 mAbs for 48 h. Flow cytometry plot is from one representative experiment. Data represent the mean ± standard error of the mean. *P ≥ 0.01, P ≥ 0.001, compared with the control group. P ≥ 0.01, compared with the Gal-9 group.

Figure 3: Gal-9 increases the expression of MMP-2 by HTR8/SVneo cells. (a and b) Flow cytometric analysis (right) and quantitation (left) of MMP-2 (a) and MMP-2 production (b) by HTR8/SVneo cells after stimulation with or without Gal-9 (1,000 ng/mL) for 48 h. Flow cytometry plot is from one representative experiment. Data represent mean ± standard error of the mean. *<i>P</i> ≥ 0.001. (c and d) Flow cytometric analysis (d) and quantitation (c) of MMP-2 production by HTR8/SVneo cells after stimulation with or without Gal-9 (1,000 ng/mL) in the presence or absence of anti-Gal-9, anti-CD44, or anti-Tim–3 mAbs for 48 h. Flow cytometry plot is from one representative experiment. Data represent the mean ± standard error of the mean. *<i>P</i> ≥ 0.01, <sup>†</sup><i>P</i> ≥ 0.001, compared with the control group. <sup>‡</sup><i>P</i> ≥ 0.01, compared with the Gal-9 group.