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  Indian J Med Microbiol
 

Figure 5: Schematic diagram of Gal-9-mediated promotion of human trophoblast cell invasiveness. Trophoblast cells secrete Gal-9, which in turn interacts with its receptor Tim-3 in trophoblast cells. Interaction of Gal-9/Tim-3 activates the p38 signaling pathway, which stimulates the expression of MMP-2 and promotes the invasion of human trophoblast cells.

Figure 5: Schematic diagram of Gal-9-mediated promotion of human trophoblast cell invasiveness. Trophoblast cells secrete Gal-9, which in turn interacts with its receptor Tim-3 in trophoblast cells. Interaction of Gal-9/Tim-3 activates the p38 signaling pathway, which stimulates the expression of MMP-2 and promotes the invasion of human trophoblast cells.