Figure 6: Histopathological changes in testicular tissue (H and E, ×400) in (1) normal control group, (2 and 3) positive control group, (4) Thymus vulgaris 4.5 mg/kg, (5) Thymus vulgaris 9 mg/kg, (6) Thymus vulgaris 18 mg/kg. The black arrows in 2: Lumen space in abnormal conditions filled with degenerated cells. The square box in 1, 4, 5, and 6: Germinal epithelium containing spermatogenic cells. The circle box in 2 and 3: Degeneration of spermatogonial cells and release of cell debris into the lumen space. The stars in 2 and 3: Destruction of the wall of seminiferous tubules. The red arrows in 3: Identifies vacuolization.